For a couple in their 20's with no fertility problems, the chance of conceiving within one month of trying naturally is around 20% to 25%, at best. Their chance of conceiving naturally over a period of 9 to 12 months is around 85%. This chance of natural conception decreases with the woman’s age, the amount of time trying to conceive, and fertility risk factors.
IVF is a type of assisted reproductive technology performed by fertility doctors. Since the first successful IVF treatment in the U.K. in 1978, five million IVF babies have been born worldwide. Of all the fertility treatments, IVF has the highest success rates for most couples. For the 10% to 15% of couples who turn out to need fertility treatment, knowing about IVF and your chances of having a baby from IVF at the outset will help you seek a fertility doctor about IVF while your chances of IVF success are still good.
In an IVF treatment, your doctor prescribes medications, often including hormonal injections, to stimulate your ovaries to produce mature eggs, monitors your ovarian stimulation and ovarian follicle development with blood tests and ultrasound, and takes the eggs out of your ovaries in a procedure called egg retrieval.
The fertilization of the sperm and egg takes place outside of the body in a laboratory dish, and the resulting embryos grow in an incubator for a few days in a nutritious broth, called culture media. Then, your doctor places a selected embryo (or embryos) directly into your uterus during embryo transfer, and you will get a pregnancy test in 10 to 14 days to see if your embryo(s) have implanted in a pregnancy.
Intrauterine insemination (IUI) is a fertility treatment that aims to optimize several factors to improve the probability of conceiving: Washing and placing motile sperm in a small volume of liquid improve sperm quality and concentration; placing washed sperm directly into the uterus bypasses potential cervical factors; timing of insemination to 24 to 36 hours prior to ovulation optimizes the timing of ovulation. The procedure requires women to have healthy fallopian tubes.
For the procedure, women who do not ovulate regularly take medication to induce ovulation of one to two eggs. Women who do ovulate take medication to cause the ovulation of at least two eggs (but no more than three eggs) to increase the chance of conceiving. Oral medication is most commonly prescribed, but injected hormonal medications can be used also. IUI results in clinical pregnancy rates of 5% to 15% with the use of oral medication. Then, 85% to 90% of those pregnancies result in live births.
IUI tends to be less expensive, because it does not require egg retrieval, embryo culture, and embryo transfer. As a result, many couples start their fertility treatment with IUI. However, the success rate of IUI also tends to be much lower for most couples. One problem with trying several IUI treatments instead of starting IVF treatment early is that your ovarian reserve continues to decline, so the later you start IVF treatment, the lower your chances of IVF success.
If you have not done IVF treatments before and are trying to decide whether to start IVF or whether to switch from IUI to IVF treatment, get your Univfy PreIVF from a participating fertility provider to find out your personalized probability of IVF success and compare that to your chances of success from one or more IUI treatments.
How does body mass index (BMI) affect my fertility and IVF success?
BMI stands for Body Mass Index, and many fertility specialists consider the optimal BMI range for conception to be 19 to 25.
What does this mean for you? Women and men often don’t realize that a healthy weight is an important fertility factor. A higher BMI can have a negative impact on your IVF success rate. While losing 5% of your body weight may be recommended if your BMI is over 25, it is also important to consider the time that it will take to lose that weight. Delaying IVF treatment can compromise your chances, as your ovarian reserve declines. Learn more about our Univfy BMI Calculator to find out your body mass index.
What is ovarian reserve, and how does it affect my fertility and IVF success?
We are glad you’re asking. Aging ovaries are the biological driving force behind decreased fertility due to age. Ovarian reserve is typically discussed in the context of declining egg supply and egg quality that comes with age. As a woman ages, her egg quality and number of eggs decrease.
But each individual woman's ovaries age at a different pace, and many factors other than age affect IVF success. Ovarian reserve can be measured indirectly through three clinical tests:
Let's learn about each of these clinical tests below.
What is Day 3 FSH, why it is so important, and how does it affect my fertility and IVF success?
FSH stands for follicle-stimulating hormone, a hormone released by your brain to control your ovarian function and menstrual cycle. Day 3 FSH is a blood test to measure the level of FSH in your bloodstream. This test is usually measured together with your estradiol level during fertility testing to assess your ovarian reserve. Estradiol is a form of the female hormone, estrogen, produced by your body. The blood tests for these two hormones–FSH and estradiol–are taken on Day 3 of your menstrual cycle (with Day 1 as the first day of full menstrual blood flow).
What are AFC and AMH, and how do they affect my fertility and IVF success?
AFC, which stands for antral follicle count, is an ultrasound test which reveals the number of antral follicles in your ovaries. Antral follicles are immature ovarian follicles that may grow and mature upon hormonal stimulation. Each follicle usually contains an egg, or oocyte. AFC is optional information that you can enter when filling out your Univfy IVF Prediction Test questionnaire. The accuracy of your test will not be affected if you do not have AFC. However, if you do have your AFC information, it should be 6 or above for you to qualify.
AMH, which stands for anti-mullerian hormone, is a hormonal blood test that is often used to help determine the starting dose for IVF medications. It estimates the egg store in your ovaries, also called ovarian reserve.
How do male fertility factors affect IVF success?
About one-third of the time, if a couple is having trouble getting pregnant, the problem may have to do with male fertility. For this reason, your doctor will usually order a semen analysis for your male partner to find out the following information:
These factors can have an impact on IVF success.
What is the predictive technology behind Univfy?
Univfy’s predictive technology originated from research conducted at Stanford University starting in 2005. Since then, Univfy has collaborated with many leading IVF clinics in the U.S. and worldwide to advance its predictive technology to serve women and their partners to learn about their personalized chances of having a baby from IVF.
Previously, Univfy developed each of its IVF Prediction Tests with data from thousands of IVF cycles and further validated (or tested) them with data from an independent group of IVF cycles. Our ongoing, rigorous research and development have now enabled us to develop and validate the Univfy PreIVF Report for each IVF center, based on its own IVF outcomes data. That means patients can now get personalized IVF success probabilities specifically validated for the IVF center that is giving the treatment. We provide transparency to our work in clinical research papers published in top medical research journals. Please see Why Univfy to learn more about Univfy's technology.
The Univfy PreIVF Report applies advanced statistical methods to assess many clinical factors specific to you and your male partner (or you alone if using donor sperm) and predicts your chances of having a baby from your first IVF treatment.
Factors include your body mass index, age, reproductive history, and the laboratory tests called serum Day 3 FSH and AMH. Additional information that can also be used by your provider includes your clinical fertility diagnoses, your male partner's sperm count, and your antral follicle count (AFC) (an ultrasound test of your ovarian reserve).
Though most relevant fertility factors are already known to be associated with IVF outcomes, Univfy is the first to apply a combination of powerful statistical methods, including the boosted tree method, to analyze these factors simultaneously to provide a more accurate and personalized IVF success rate prediction.
How does the Univfy PreIVF Report differ from other prediction tools, such as the SART calculator?
The Univfy PreIVF Report is the ONLY validated IVF success prediction test that uses a comprehensive set of reproductive health data specific to you and your partner, AND validated for your fertility center based on its IVF performance outcomes data. Other IVF calculators use age-based estimates that are not validated, or in other words, proven, or do not use health data tailored to the individual. Many free, online calculators technically do not provide "predictions”, and are merely giving averages. Further, the Univfy PreIVF Report powers your fertility provider's IVF refund program to help five times more patients qualify for an IVF refund offer. We go all the way to help you get the most out of IVF while helping you to keep your IVF costs low.
HELPS YOU MAKE DECISIONS AT KEY STAGES IN YOUR FERTILITY TREATMENT—The Univfy PreIVF Report helps you make more informed decisions about your treatment recommendations: When to start IVF, when to stop IUI and start IVF, whether to do another IVF after a failed IVF treatment, and to help evaluate your personalized risk of multiple births when considering elective single embryo transfer.
HIGHLY ACCURATE AND PERSONALIZED PREDICTIONS--The Univfy PreIVF Report is the only validated IVF prediction report that is personalized to the patient and validated for a fertility provider. Univfy delivers highly accurate, personalized predictions of your IVF success by using clinical factors, identified by scientific research to be the most important in predicting IVF success. Clinical factors used by Univfy tests include:
TESTED AND PROVEN--The Univfy PreIVF Report is validated according to established standards for the predictive sciences and Univfy has further established a very high bar for validating predictive models specifically for IVF outcomes. Our performance metrics are published in top peer-reviewed clinical research journals.
How accurate is the Univfy PreIVF Report?
We measure the power of our prediction models in different ways. For example, we measure our tests’ prediction power and ability to distinguish patients with different probabilities of IVF treatment success, versus conventional average IVF success rates based on age alone. Also, we measure how useful a test would be in day-to-day fertility practice by computing the percentage of patients that would receive a different predicted probability from using Univfy tests, compared to predictions based on age alone. Finally, we measure and report the prediction error in each report.
Who are Univfy’s researchers and collaborators?
Univfy has built collaborative research partnerships with top fertility providers in the US and internationally renowned fertility researchers and clinical experts. This global initiative helps Univfy broaden the scope and increase the impact of our fertility research. For more detailed information, visit Find a Fertility Provider, Why Univfy and About Us to learn more about Univfy-powered IVF providers, research and collaborators.
What is Your Fertility?
Your Fertility offers original, interactive, multimedia fertility health content that meets the practical needs of women and men anywhere on their fertility path. Your Fertility offers top Fertility Articles, Fertility Guides, the Fertility Deep Dive Series, and Univfy Fertility Calculators (see more below).
How do I use Univfy’s free online calculators?
Univfy Fertility Calculators provide essentials in an interactive and personalized format to address the needs of women at different points on their fertility path.
The Univfy Ovulation Calculator serves to help boost chances of success for women with no fertility problems. This calculator will determine your most fertile days and when you should start using your ovulation predictor kits.
When trying to conceive, pinpointing the most fertile days in your cycle can boost chances and shorten the number of months it takes to get pregnant. Enter the dates (up to your last four cycles), and the calculator will determine your average cycle length and the most fertile days in your cycle. If you are using one of four popular ovulation predictor kits, the calculator will also tell you the best day in your cycle to start using the kit.
The Univfy Body Mass Index Calculator helps you understand how your weight affects your chances for conceiving and your pregnancy health. This calculator will determine your body fat measure and provides fertility and pregnancy health information specific to your level of BMI.
Enter your height and weight into this calculator to find out your BMI and whether it is in a healthy range for getting pregnant. You will learn about the impact of weight loss on your pregnancy health prior to conceiving. If you do not need to lose weight, you can save that precious time to make the most of your fertility.
What is the Univfy IVF Cost Calculator, and how is it different from other IVF cost calculators?
The Univfy IVF Cost Calculator is the only online calculator that uses your personal IVF success rate and IVF cost to compare financial payment options and IVF packages directly.
For example, this calculator will help you compare your actual cost of having an IVF baby if you purchase IVF cycles one-at-a-time, versus multi-cycle discount packages or refund packages (also called risk-share).
Your overall IVF cost to have an IVF baby can be drastically different depending on your IVF success rate. That’s why an accurate and personalize IVF success rate will help provide an accurate IVF cost estimate. Seeing your odds and costs clearly laid out can help you make the best financial and health decisions for your family.
How do I contact Univfy Customer Support?
If you have any questions, please click here, or contact Unvify Customer Support at 1-877-9-UNIVFY (1-877-986-4839) between the hours of 8 a.m. and 4 p.m., U.S. Pacific time, Monday through Friday, excluding major holidays. If you prefer to contact us by email, please send your inquiry to firstname.lastname@example.org. We will make our best effort to respond within one business day. For your privacy, please refrain from including any personal medical information in your email or voice message.
Can my physician contact you about my Univfy test report or with any other questions?
A: Yes. Please ask your physician to call Univfy Customer Support at 1-877-9-UNIVFY (1-877-986-4839). They can also contact us via this form, by visiting our website at www.univfy.com, or by emailing us at email@example.com. We will make our best effort to respond within one business day. For your privacy, please ask them not to include any personal identifiers in their email or voice message.
What are my privacy rights, and how are they protected?
What are Univfy's Website policies?
If you have questions about any of the above policies, please contact us via email at firstname.lastname@example.org.
The Registered User Agreement applies to Registered Users only, and explains the terms and conditions for using pages that require secure login at Univfy's website (www.univfy.com), including registration, viewing of Test Questionnaire, test selection, payment for prediction test, test questionnaire, and data review page. In addition, the Registered User Agreement explains the rules for using any pages or functionalities of the Univfy IVF Prediction Test Dashboard, such as viewing of incomplete tests, completed tests, and communicating with Univfy Customer Support.